Sena Research is a pioneering company based in Marietta, GA, specializing in the development and marketing of innovative selenium technologies for X-ray and neutron crystal structure determination and function studies of nucleic acids and protein-nucleic acid complexes. Their cutting-edge methodologies using selenium-derivatized or modified nucleic acids, known as SeNA, offer exciting advancements in molecular packing and crystallization, resulting in faster crystal growth, broader buffer conditions, larger crystals, and high-diffraction quality. These groundbreaking technologies have proven to be superior to conventional methods, enabling more efficient phase determination, higher diffraction resolution, and greater molecular stability during X-ray or neutron radiation and diffraction data collection. With a mission to advance scientific understanding at the molecular level, Sena Research has successfully developed patented selenium technologies over the course of 22 years. By replacing oxygen atoms with selenium in nucleic acids, their innovative derivatization strategies provide several advantages over traditional methods, such as selective introduction of selenium to various positions and avoidance of structure and function disruption. This breakthrough approach facilitates the determination of three-dimensional structures of nucleic acid molecules and their protein complexes, which is crucial for advancing drug development and improving patient care. Through their expertise in X-ray and neutron crystallography, Sena Research is at the forefront of discovering novel drugs targeting nucleic acids, including RNA and protein-nucleic acid complexes.Generated from the website

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