The Lee Oesterreich Lab, led by Dr. Adrian Lee and Dr. Steffi Oesterreich, is dedicated to studying the molecular basis of breast cancer development and resistance to therapy. Their research aims to improve precision medicine and outcomes for breast cancer patients by utilizing a systems biology approach, incorporating single cell and bulk sequencing, computational methods, and biological models to identify and validate new drivers and therapeutic targets. With a focus on understanding invasive lobular cancer (ILC), the second most common but understudied histological subtype of breast cancer, the lab also investigates mechanisms of resistance to endocrine therapy and new approaches to blocking breast cancer metastasis. They collaborate with a large network of clinicians and nurses to analyze human specimens and large biomedical and genomic datasets, including electronic health record data. The lab maintains a strong training environment and prioritizes a healthy lab environment to ensure high productivity and rigor.Generated from the website

Labar, Amy Sala MD

Paradis Irvin MD

Michael Fine MD

Bruce L Rollman, MD - University of Pittsburgh